Nobel Intent: Have we had effective anti-malarial drugs all along?

...it will work with complex and poorly understood disease targets. Malaria ranks pretty high up on the scale of complex and poorly understood diseases, ... the majority of the drugs they tested have already been approved by the FDA, meaning they've passed rigorous safety screening, and would be relatively inexpensive to bring to market for a new use.

Nearly 200 drugs were identified that reduced parasite cell division by over 50 percent. The authors focused in on an antihistamine called astemizole, "