ScienceDaily: How HIV 'Exhausts' Killer T Cells

ScienceDaily: How HIV 'Exhausts' Killer T Cells:

"American and South African scientists working at the epicenter of the AIDS epidemic in South Africa have discovered how the human immunodeficiency virus (HIV) 'exhausts' killer T cells that would otherwise attack the virus. The researchers found that HIV can simply “turn off” fully functional T cells by flipping a molecular switch on the cells. In test tube studies, however, the scientists showed that they could reinvigorate the killer T cells by blocking that inhibitory switch, which is called programmed death-1 (PD-1)."